N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine CAS NO.1231929-97-7

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Product Name:    Abemaciclib
Synonyms:    Abemaciclib, >=98%;Abemaciclib;abemaciclib(CDK 4/6 inhibitor);Abemaciclib (LY2835219);Bemaciclib(LY2835219, abemaciclib);CDK4/6 dual inhibitor;LY 2835219 (free base);LY2835219 (free base)
CAS:    1231929-97-7
form     solid
color     Off-white to yellow
Raw materials    EthaniMidaMide, N-(4-broMo-2,6-difluorophenyl)-N'-(1-Methylethyl)--->4-Bromo-2,6-difluoroaniline-->2-Bromopyridine-5-carbaldehyde-->Piperazine, 1-[(6-broMo-3-pyridinyl)Methyl]-4-ethyl--->N-Isopropylacetamide-->1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)--->1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)--->4-AMINO-3,5-DIFLUOROACETOPHENONE-->5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine-->6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole-->1-Ethylpiperazine-->2,6-Difluoroaniline